The goal of this research was to understand the impact of different work arrangements (e.g. remote, hybrid, or on-premise) on employee well-being, considering the changes brought about by the pandemic. The study utilized a large sample of white-collar employees, with a focus on the mediating role of perceived flexibility and the moderating effect of managerial support in the relationship between work arrangements and employee well-being. As companies currently (re-)design their work arrangements there is a lot of insecurity on how especially remote and hybrid work influences the workforce and some companies are caught in a zig-zag course of overhauling their policies. Our findings suggest that employee well-being is mediated by location flexibility and work-life balance. However, the study also reveals challenges faced by remote workers, as the intense telecommuting was associated with lower employee well-being. The study also emphasizes the major role of managerial support in promoting employee well-being.