This study examines four variables namely leadership style, job satisfaction, motivation, and nurse performance. The purpose of this study is to analyze and explain the effect of leadership and job satisfaction on nurse performance by testing individual motivation as intervening. The research respondents were nurses with government employees who worked at Regional Public Hospital (RSUD) Dr. Wahidin Sudiro Husodo Mojokerto city, Indonesia. A total of 117 were sampled for this study. The analysis technique is descriptive and linear regression for confirmation on a structural equation model built by the researcher. The quantitative approach was chosen to explain the influence between research variables. Data collection used a questionnaire. The results of this study found that the leadership style had led to individual motivational behaviour which ultimately had a positive impact on nurse performance. Nurse Job satisfaction affects individual motivation and nurse performance.